A Phase Ib, Open-Label, Multicenter Study To Investigate The Pharmacokinetics, Safety, And Tolerability Of Subcutaneous Ocrelizumab Administration In Patients With Multiple Sclerosis
Latest Information Update: 26 Mar 2025
At a glance
- Drugs Ocrelizumab (Primary) ; Ocrelizumab (Primary) ; Hyaluronidase
- Indications Multiple sclerosis
- Focus Adverse reactions; Pharmacokinetics
- Acronyms Ocarina I
- Sponsors Roche
- 18 Apr 2024 Results assessing safety, tolerability and pharmacokinetic data in patients with relapsing and primary progressive multiple sclerosis (RMS/PPMS), to select the appropriate OCR subcutaneous (SC) dose for OCARINA II, were presented at the 76th Annual Meeting of the American Academy of Neurology 2024.
- 17 Apr 2024 Planned primary completion date changed from 30 Jun 2023 to 20 Jun 2025.
- 02 Mar 2024 Results assessing the OCR safety, tolerability and pharmacokinetics in patients with RMS/PPMS, to select the appropriate OCR SC dose for OCARINA II, presented at the Americas Committee for Treatment and Research in Multiple Sclerosis Forum 2024.