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The Mechanism of Action Underlying Ketamine's Antidepressant Effects: An Investigation of the AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression

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Trial Profile

The Mechanism of Action Underlying Ketamine's Antidepressant Effects: An Investigation of the AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 13 Jun 2025

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At a glance

  • Drugs Ketamine (Primary) ; Perampanel (Primary)
  • Indications Major depressive disorder
  • Focus Therapeutic Use

Most Recent Events

  • 17 Feb 2025 Planned End Date changed from 1 Feb 2025 to 1 Feb 2026.
  • 17 Feb 2025 Planned primary completion date changed from 1 Feb 2025 to 1 Feb 2026.
  • 15 Feb 2022 Planned End Date changed from 1 Feb 2022 to 1 Feb 2025.

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