Trial Profile

A phase 2, placebo-controlled, 28-day study of PTI-428 in patients with cystic fibrosis with at least one F508del mutation

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 17 Jul 2025

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At a glance

Drugs Dirocaftor (Primary) ; Nesolicaftor (Primary) ; Posenacaftor (Primary)
Indications Cystic fibrosis
Focus Adverse reactions; Therapeutic Use
Sponsors Kineta; Proteostasis Therapeutics; TuHURA Biosciences; Yumanity Therapeutics

Most Recent Events

30 Jun 2025 According to TuHURA Biosciences media release, Kineta has been acquired and merged into TuHURA Biosciences.
19 Dec 2022 According to a Kineta media release, Yumanity Therapeutics was merged with Kineta to form Kineta.
17 Dec 2019 Results presened in a Proteostasis Therapeutics Media Release.

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