Trial Profile

ISILI (In Situ Immunotherapy of LIver Metastases): An Openlabel, Dose-finding, Phase I Study of Intratumoral Ipilimumab and TLR4 Agonist GLA-SE in Combination With Systemic Nivolumab and Chemotherapy (FOLFOX Regimen) in Patients With Colorectal Liver Metastases.

Status: Withdrawn prior to enrolment

Phase of Trial: Phase I

Latest Information Update: 04 Nov 2021

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At a glance

Drugs Glycopyranosyl lipid adjuvant (Primary) ; Ipilimumab (Primary) ; Nivolumab (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
Indications Adenocarcinoma; Colorectal cancer
Focus Adverse reactions
Acronyms ISILI

12 Feb 2020 Planned End Date changed from 1 Jun 2025 to 12 Feb 2020.
12 Feb 2020 Planned primary completion date changed from 1 Jun 2021 to 12 Feb 2020.
12 Feb 2020 Status changed from active, no longer recruiting to withdrawn prior to enrolment.

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