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A Randomized, Double-blind, Placebo-controlled Phase 2b Study to Assess the Efficacy, Immunogenicity and Safety of an Ad26.RSV.preF-based Regimen in the Prevention of RT PCR-confirmed RSV-mediated Lower Respiratory Tract Disease in Adults Aged 65 Years and Older

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A Randomized, Double-blind, Placebo-controlled Phase 2b Study to Assess the Efficacy, Immunogenicity and Safety of an Ad26.RSV.preF-based Regimen in the Prevention of RT PCR-confirmed RSV-mediated Lower Respiratory Tract Disease in Adults Aged 65 Years and Older

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 16 Sep 2024

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At a glance

  • Drugs JNJ 64400141 (Primary)
  • Indications Respiratory syncytial virus infections; Respiratory tract disorders
  • Focus Proof of concept; Therapeutic Use
  • Acronyms CYPRESS
  • Sponsors Janssen Vaccines and Prevention B.V

    • Most Recent Events

    • 01 Sep 2024 Results assessing vaccine efficacy of Ad26RSV-preF were presented in The Lancet Infectious Diseases.
    • 07 May 2024 Status changed to discontinued by the sponsor for strategic reprioritization.
    • 21 Jul 2023 Status changed from active, no longer recruiting to completed.

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