A single arm multi-centre translational proof of concept study investigating the safety and efficacy of alternating lorlatinib with crizotinib in a pre-treated advanced ALK-rearranged non-small cell lung cancer population with disease progression on a 2nd generation ALK tyrosine kinase inhibitor
Latest Information Update: 11 Oct 2021
At a glance
- Drugs Crizotinib (Primary) ; Lorlatinib (Primary)
- Indications Adenocarcinoma; Non-small cell lung cancer
- Focus Proof of concept; Therapeutic Use
- Acronyms ALKternate
Most Recent Events
- 14 Sep 2021 Trial design presented at the 2021 World Conference on Lung Cancer
- 04 Dec 2020 Planned End Date changed from 13 Dec 2021 to 31 Dec 2022.
- 10 Sep 2019 Trial design presented at the 20th World Conference on Lung Cancer.