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Efficacy and Safety of Semaglutide 2.0 mg s.c. Once-weekly Compared to Semaglutide 1.0 mg s.c. Once-weekly in Subjects With Type 2 Diabetes

Trial Profile

Efficacy and Safety of Semaglutide 2.0 mg s.c. Once-weekly Compared to Semaglutide 1.0 mg s.c. Once-weekly in Subjects With Type 2 Diabetes

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 15 Feb 2023

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At a glance

  • Drugs Semaglutide (Primary)
  • Indications Type 2 diabetes mellitus
  • Focus Registrational; Therapeutic Use
  • Acronyms SUSTAIN FORTE
  • Sponsors Novo Nordisk
  • Most Recent Events

    • 23 Sep 2022 Results of post hoc analysis evaluating the effect of semaglutide 2 mg vs 1mg on glycaemic control and BW across a broader range of baselinedemographic subgroups, presented at the 58th Annual Meeting of the European Association for the Study of Diabetes..
    • 15 Aug 2022 Results from SURPASS-2 and SUSTAIN FORTE trials published in the Diabetes, Obesity and Metabolism
    • 28 Mar 2022 According to a Novo Nordisk media release, based on the data from this trial, the US Food and Drug Administration (FDA) has approved a 2.0 mg dose of Ozempic (once-weekly semaglutide subcutaneous injection), a glucagon-like peptide-1 (GLP-1) analogue for the treatment of adults with type 2 diabetes. Ozempic 2.0 mg is now approved in the US, the EU, Canada and Switzerland.

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