Sequential B Cell/T Cell Therapy to Re-induce Humoral Immune TOLErance in ACPA- Positive Rheumatoid Arthritis A Prospective, Randomized Controlled Open Label Single-centre Clinical Trial in Adult Subjects With Active ACPA-positive Rheumatoid Arthritis Failing Methotrexate
Latest Information Update: 22 Jul 2024
At a glance
- Drugs Abatacept (Primary) ; Rituximab (Primary)
- Indications Rheumatoid arthritis
- Focus Pharmacodynamics
- Acronyms TOLERA
Most Recent Events
- 15 Jun 2024 Results evaluating the effect of a sequential RTX/ABA treatment to lower ACPA titers, eliminate auto-antibody production and attenuate disease activity in RA patients in comparison to RTX alone, presented at the 25th Annual Congress of the European League Against Rheumatism
- 13 Aug 2022 Status changed from recruiting to completed.
- 20 Jun 2019 New trial record