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A Two-Part, Open-Label, Fixed-Sequence Study to Evaluate the Effect of Multiple Doses of Itraconazole and Rifampin on the Single-Dose Pharmacokinetics of Mitapivat Sulfate (AG-348) in Healthy Adult Subjects

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Trial Profile

A Two-Part, Open-Label, Fixed-Sequence Study to Evaluate the Effect of Multiple Doses of Itraconazole and Rifampin on the Single-Dose Pharmacokinetics of Mitapivat Sulfate (AG-348) in Healthy Adult Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 24 Oct 2019

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At a glance

  • Drugs Mitapivat (Primary) ; Itraconazole; Rifampicin
  • Indications Inborn error metabolic disorders; Sickle cell anaemia; Thalassaemia
  • Focus Pharmacokinetics
  • Sponsors Agios Pharmaceuticals

Most Recent Events

  • 18 Sep 2019 Status changed from active, no longer recruiting to completed.
  • 29 Aug 2019 Status changed from recruiting to active, no longer recruiting.
  • 15 Jul 2019 Status changed from not yet recruiting to recruiting.

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