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A Phase II, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Safety and Efficacy of Cemdisiran (ALN-CC5) Following Withdrawal of Chronic Eculizumab Therapy in Patients With Atypical HUS at High Risk of Recurrence

Trial Profile

A Phase II, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Safety and Efficacy of Cemdisiran (ALN-CC5) Following Withdrawal of Chronic Eculizumab Therapy in Patients With Atypical HUS at High Risk of Recurrence

Status: Withdrawn prior to enrolment
Phase of Trial: Phase II

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs Cemdisiran (Primary)
  • Indications Atypical Haemolytic Uraemic Syndrome
  • Focus Therapeutic Use
  • Acronyms DANCE

Most Recent Events

  • 08 Mar 2021 Planned End Date changed from 1 Feb 2024 to 1 Mar 2024.
  • 08 Mar 2021 Planned primary completion date changed from 1 Feb 2024 to 1 Jan 2024.
  • 08 Mar 2021 Status changed from not yet recruiting to withdrawn prior to enrolment as sponsor has not received the economic support necessary for the study conduction due to the COVID global pandemic.

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