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A Randomized, Open Label, Phase III Study of Overall Survival Comparing Pembrolizumab (MK-3475) Versus Platinum Based Chemotherapy in Treatment Naïve Subjects With PD-L1 Positive Advanced or Metastatic Non-Small Cell Lung Cancer (Keynote 042)

Trial Profile

A Randomized, Open Label, Phase III Study of Overall Survival Comparing Pembrolizumab (MK-3475) Versus Platinum Based Chemotherapy in Treatment Naïve Subjects With PD-L1 Positive Advanced or Metastatic Non-Small Cell Lung Cancer (Keynote 042)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 19 Sep 2023

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At a glance

  • Drugs Pembrolizumab (Primary) ; Carboplatin; Paclitaxel; Pemetrexed
  • Indications Bladder cancer; Non-small cell lung cancer; Skin cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms China Extension Study
  • Sponsors Merck Sharp & Dohme; Merck Sharp & Dohme Corp.
  • Most Recent Events

    • 27 Sep 2022 Status changed from active, no longer recruiting to completed..
    • 18 May 2022 Planned End Date changed from 5 Jul 2022 to 12 Sep 2022.
    • 15 Mar 2022 Planned End Date changed from 7 Mar 2022 to 5 Jul 2022.

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