Trial Profile

A Phase Ib Study of Safety and Efficacy of APG-1252 in Combination With Osimertinib (AZD9291) in EGFR TKI Resistant NSCLC Patients

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 02 Jun 2025

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At a glance

Drugs Osimertinib (Primary) ; Palcitoclax (Primary)
Indications Non-small cell lung cancer
Focus Adverse reactions
Sponsors Ascentage Pharma

Most Recent Events

28 May 2025 Planned End Date changed from 1 Jun 2025 to 1 Jun 2026.
28 May 2025 Planned primary completion date changed from 1 Dec 2024 to 1 Dec 2025.
24 Oct 2023 Updated (As of Feb16,2023, n=64) safety and efficacy results of this combination therapy presented at the 48th European Society for Medical Oncology Congress

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