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A Phase 2 Open-Label, Multicenter Study Evaluating the Safety and Efficacy of Axicabtagene Ciloleucel in Combination With Rituximab in Participants With Refractory Large B-Cell Lymphoma (ZUMA-14)

Trial Profile

A Phase 2 Open-Label, Multicenter Study Evaluating the Safety and Efficacy of Axicabtagene Ciloleucel in Combination With Rituximab in Participants With Refractory Large B-Cell Lymphoma (ZUMA-14)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 22 Feb 2024

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At a glance

  • Drugs Axicabtagene ciloleucel (Primary) ; Rituximab (Primary) ; Cyclophosphamide; Fludarabine
  • Indications B-cell lymphoma
  • Focus Therapeutic Use
  • Acronyms ZUMA-14
  • Sponsors Gilead Sciences

Most Recent Events

  • 06 Jun 2023 Results from NCT03391466, NCT03761056, NCT04002401, exploring the value of ctDNA to predict outcomes in LBCL after axi-cel across lines of treatment, presented at the 59th Annual Meeting of the American Society of Clinical Oncology
  • 10 Feb 2023 Status changed from active, no longer recruiting to completed.
  • 23 Jun 2022 Planned End Date changed from 1 Jun 2036 to 1 Dec 2022.

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