A Phase 3 Randomized, Open-Label, Multicenter Study Comparing Zanubrutinib (BGB-3111) Plus Rituximab Versus Bendamustine Plus Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma Who Are Ineligible for Stem Cell Transplantation
Latest Information Update: 06 Mar 2025
At a glance
- Drugs Zanubrutinib (Primary) ; Bendamustine; Rituximab
- Indications Mantle-cell lymphoma
- Focus Registrational; Therapeutic Use
- Acronyms MANGROVE
- Sponsors BeOne Medicines
Most Recent Events
- 27 Feb 2025 According to BeiGene media release, company anticipate an interim analysis of progression-free survival for the Phase 3 MANGROVE study in TN mantle cell lymphoma (MCL) in the second half of 2025.
- 09 Jan 2024 Status changed from recruiting to active, no longer recruiting.
- 05 Oct 2021 Planned End Date changed from 1 Aug 2026 to 1 Dec 2027.