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An Open-Label Pilot Study of Losmapimod to Evaluate the Safety, Tolerability, and Changes in Biomarker and Clinical Outcome Assessments in Subjects With Facioscapulohumeral Muscular Dystrophy 1 (FSHD1) With Extension

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Trial Profile

An Open-Label Pilot Study of Losmapimod to Evaluate the Safety, Tolerability, and Changes in Biomarker and Clinical Outcome Assessments in Subjects With Facioscapulohumeral Muscular Dystrophy 1 (FSHD1) With Extension

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 04 Dec 2024

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At a glance

  • Drugs Losmapimod (Primary)
  • Indications Facioscapulohumeral muscular dystrophy
  • Focus Adverse reactions
  • Acronyms FSHD
  • Sponsors Fulcrum Therapeutics
  • Most Recent Events

    • 02 Dec 2024 Status changed from active, no longer recruiting to discontinued. ( Sponsor Decision )
    • 15 Jul 2024 Results (n=14) from the main portion of the study, assessing the safety, tolerability and changes in biomarker and clinical outcome assessments in patients with FSHD1, published in the Journal of the Neurological Sciences
    • 05 Jul 2023 Planned End Date changed from 1 Jan 2024 to 1 Jan 2026.

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