Trial Profile

A 64-week, Two-arm, Randomized, Double-masked, Multicenter, Phase IIIb Study Assessing the Efficacy and Safety of Brolucizumab 6 mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen in Patients With Neovascular Agerelated Macular Degeneration (TALON)

Status: Completed

Phase of Trial: Phase III

Latest Information Update: 02 Mar 2026

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At a glance

01 Feb 2026 Results comparing the efficacy and safety of brolucizumab 6 mg and aflibercept 2 mg in patients with neovascular age-related macular degeneration (nAMD) using an identical 4-week adjustment Treat-and-Extend regimen were published in the Eye.
26 Nov 2022 Status changed from active, no longer recruiting to completed.
20 Oct 2022 The trial has been completed in Sweden, according to European Clinical Trials Database record.

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