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A Phase III, Randomized, Multicenter, Open-Label Study in Adolescent and Adult Participants Comparing the Efficacy and Safety of Gepotidacin to Ceftriaxone Plus Azithromycin in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria Gonorrhoeae

Trial Profile

A Phase III, Randomized, Multicenter, Open-Label Study in Adolescent and Adult Participants Comparing the Efficacy and Safety of Gepotidacin to Ceftriaxone Plus Azithromycin in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria Gonorrhoeae

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 31 May 2024

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At a glance

  • Drugs Gepotidacin (Primary) ; Azithromycin; Ceftriaxone
  • Indications Gonococcal urethritis; Gonorrhoea
  • Focus Registrational; Therapeutic Use
  • Acronyms EAGLE-1
  • Sponsors GlaxoSmithKline; GlaxoSmithKline Research & Development; GSK

Most Recent Events

  • 26 Feb 2024 Results presented in a GSK Media Release.
  • 26 Feb 2024 According to a GSK media release, detailed results from the EAGLE-1 trial will be presented at an upcoming scientific meeting and shared with global health authorities.
  • 26 Feb 2024 Primary endpoint (Number of participants with culture-confirmed bacterial eradication of Neisseria gonorrhoeae from the urogenital site at the Test-of-Cure (TOC)) has been met, according to a GSK media release.

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