Trial Profile

Targeted Therapy With CDK4/6 Inhibitors in Chemo- Refractory/Relapsed, Rb Wild-type Extensive Small Cell Lung Cancer (SCLC), Large Cell Neuroendocrine Lung Cancer, Extrapulmonary Small Cell Cancers and Other High Grade Neuroendocrine Cancers of the Lung, an Open Label Phase 2 Trial.

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 15 Dec 2025

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At a glance

Drugs Abemaciclib (Primary)
Indications Neuroendocrine carcinoma; Retinoblastoma; Small cell lung cancer
Focus Therapeutic Use

02 Dec 2025 Status changed from recruiting to active, no longer recruiting.
05 Jun 2025 Planned End Date changed from 1 Jun 2025 to 1 Dec 2025.
05 Jun 2025 Planned primary completion date changed from 1 Jun 2025 to 1 Dec 2025.

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