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A Phase 1b/2, Randomised, Placebo-controlled, Dose-ranging Study to Evaluate Safety, Tolerability and Immunogenicity of a Chimpanzee Adenovirus (ChAdOx1)-Vectored Multigenotype High Risk Human Papillomavirus (hrHPV) Vaccine and Modified Vaccinia Ankara (MVA)-Vectored Multigenotype hrHPV Vaccine in Women With Low-grade HPV-related Cervical Lesions

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Trial Profile

A Phase 1b/2, Randomised, Placebo-controlled, Dose-ranging Study to Evaluate Safety, Tolerability and Immunogenicity of a Chimpanzee Adenovirus (ChAdOx1)-Vectored Multigenotype High Risk Human Papillomavirus (hrHPV) Vaccine and Modified Vaccinia Ankara (MVA)-Vectored Multigenotype hrHPV Vaccine in Women With Low-grade HPV-related Cervical Lesions

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 02 Aug 2024

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At a glance

  • Drugs MVA-HPV (Primary) ; VTP 200 (Primary)
  • Indications Human papillomavirus infections
  • Focus Adverse reactions; First in man
  • Acronyms APOLLO
  • Sponsors Barinthus Biotherapeutics

Most Recent Events

  • 18 Apr 2024 Results presented in a Barinthus Biotherapeutics Media Release.
  • 20 Mar 2024 According to a Barinthus Biotherapeutics media release, company to announce final results of this trial in Q2 2024.
  • 18 Jan 2024 Status changed from active, no longer recruiting to completed.

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