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A Phase 2b, Open-label, Efficacy and Safety Study of ABX464 as Maintenance Therapy in Patients With Moderate to Severe Ulcerative Colitis

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Trial Profile

A Phase 2b, Open-label, Efficacy and Safety Study of ABX464 as Maintenance Therapy in Patients With Moderate to Severe Ulcerative Colitis

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 29 Jan 2025

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At a glance

  • Drugs Obefazimod (Primary)
  • Indications Ulcerative colitis
  • Focus Therapeutic Use
  • Sponsors Abivax

    • Most Recent Events

    • 23 Jan 2025 According to an Abivax media release, company today announced that scientific abstracts including data from this trial, will be presented at The European Crohn's and Colitis Organization's (ECCO's) 20th Annual Congress as part of scientific exchange, taking place Feb 19-22, 2025, in Berlin, Germany.
    • 15 Jul 2024 According to an Abivax media release, in an interim analysis as of July 31, 2023, of the 71 eligible patients, 63 completed their 48-week visit, 84% (53 of 63 patients) achieved disease control defined as stable or improved Modified Mayo Score on 25mg once-daily obefazimod. No new safety signals were detected in UC patients treated up to five years with oral, once daily obefazimod.
    • 13 Feb 2024 According to an Abivax media release, data from this study will be presented at the 19th Congress of the European Crohn's and Colitis Organisation (ECCO) on February 21-24, 2024, in Stockholm, Sweden.

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