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An Open-label Study of the Efficacy and Safety of SYNB1618 and SYNB1934 in Patients With Phenylketonuria (SynPheny-1)

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Trial Profile

An Open-label Study of the Efficacy and Safety of SYNB1618 and SYNB1934 in Patients With Phenylketonuria (SynPheny-1)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 29 Mar 2023

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At a glance

  • Drugs Labafenogene marselecobac (Primary) ; SYNB-1618 (Primary)
  • Indications Phenylketonuria
  • Focus Proof of concept; Therapeutic Use
  • Acronyms SynPheny-1
  • Sponsors Synlogic
  • Most Recent Events

    • 20 Mar 2023 Primary endpoint has been met. (Changes from baseline in labeled Phe (D5-Phe) in plasma), according to an Synlogic media release.
    • 20 Mar 2023 According to an Synlogic media release, data from this study were presented at the Society for Inherited Metabolic Disorders (SIMD) 44th Annual Meeting, Dr. Jerry Vockley.
    • 07 Mar 2023 According to Synlogic media release, company announced that it will present a podium presentation of poster at the Society of Inherited Metabolic Disorders (SIMDD) 44th Annual Meeting in Salt Lake City, Utah on 19th March 2023.

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