Trial Profile

A Phase I Study With Expansion Cohort of Concurrent GDC-0084 With Radiation Therapy for Patients With Solid Tumor Brain Metastases or Leptomeningeal Metastases Harboring PI3K Pathway Mutations

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 22 Apr 2025

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At a glance

Drugs Paxalisib (Primary)
Indications Brain metastases; Meningeal carcinomatosis; Solid tumours
Focus Adverse reactions

Most Recent Events

17 Apr 2025 Planned End Date changed from 1 Dec 2025 to 1 Dec 2026.
17 Apr 2025 Planned primary completion date changed from 1 Dec 2025 to 1 Dec 2026.
02 Oct 2024 According to a Kazia Therapeutics media release, Additional data, including circulating tumor DNA (ctDNA) from this study will be presented at an upcoming 2024 scientific congress

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