Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

A Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study to Assess the Clinical Efficacy of ISIS 721744, a Second-Generation Ligand-Conjugated Antisense Inhibitor of Prekallikrein, in Patients With Hereditary Angioedema

Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study to Assess the Clinical Efficacy of ISIS 721744, a Second-Generation Ligand-Conjugated Antisense Inhibitor of Prekallikrein, in Patients With Hereditary Angioedema

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 24 Feb 2025

Price :
$35 *
Note:
  • Adis is an information provider.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our trial profile at the time of purchase.
  • A link to download a PDF version of the trial profile will be included in your email receipt.

At a glance

  • Drugs Donidalorsen (Primary)
  • Indications Hereditary angioedema
  • Focus Therapeutic Use
  • Sponsors Ionis Pharmaceuticals

Most Recent Events

  • 17 Mar 2022 Results assessing impact on quality of life following treatment with plasma prekallikrein targeted Oligonucleotide Antisense therapy in Hereditary Angioedema Patients,published in the New England Journal of Medicine
  • 16 Mar 2022 According to an Ionis Pharmaceuticals media release, results published in New England Journal of Medicine
  • 16 Mar 2022 Results published in the Ionis Pharmaceuticals Media Release

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top