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A Randomized, Double-Blind, Multicenter, Phase III Clinical Study of HLX10 (Recombinant Anti-PD-1 Humanized Monoclonal Antibody Injection) + Chemotherapy (Carboplatin Nanoparticle Albumin Bound (Nab)-Paclitaxel) vs Chemotherapy (Carboplatin Nab-Paclitaxel) as First-Line Therapy for Locally Advanced or Metastatic Squamous Non Small Cell Lung Cancer (NSCLC)

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Trial Profile

A Randomized, Double-Blind, Multicenter, Phase III Clinical Study of HLX10 (Recombinant Anti-PD-1 Humanized Monoclonal Antibody Injection) + Chemotherapy (Carboplatin Nanoparticle Albumin Bound (Nab)-Paclitaxel) vs Chemotherapy (Carboplatin Nab-Paclitaxel) as First-Line Therapy for Locally Advanced or Metastatic Squamous Non Small Cell Lung Cancer (NSCLC)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 03 Jan 2025

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At a glance

  • Drugs Serplulimab (Primary) ; Carboplatin; Paclitaxel
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms ASTRUM-004
  • Sponsors Shanghai Henlius Biotech

Most Recent Events

  • 08 Aug 2024 According to Henlius Biopharmaceuticals media release, data from this trial will be presented at 2024 European Society of Medical Oncology (ESMO) Congress
  • 12 Feb 2024 Results for safety and efficacy, published in the Cancer Cell
  • 05 Jan 2024 According to a Shanghai Henlius Biotech media release, data from this study were published in Cancer Cell.

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