Trial Profile

A Multicentre Phase II, Open-label, Non-randomized Study Evaluating Platinum-Pemetrexed-Atezolizumab (+/- Bevacizumab) for Patients With Stage IIIB/IV Non-squamous Non-small Cell Lung Cancer With EGFR Mutations, ALK Rearrangement or ROS1 Fusion Progressing After Targeted Therapies

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 06 Jun 2025

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At a glance

Drugs Atezolizumab (Primary) ; Bevacizumab (Primary) ; Carboplatin (Primary) ; Cisplatin (Primary) ; Pemetrexed (Primary)
Indications Non-small cell lung cancer
Focus Therapeutic Use

08 Aug 2024 Planned End Date changed from 1 Jun 2024 to 1 Jun 2025.
01 Jul 2024 Results (n=149) assessing the safety and patient reported outcomes (PROs) of the PPA and PPAB cohorts in this study, published in the Lung Cancer
13 Sep 2022 Results presented at the 47th European Society for Medical Oncology Congress

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