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Phase 1b/2 Study to Evaluate Antibody-Drug Conjugate Sacituzumab Govitecan in Combination With PARP Inhibitor Talazoparib in Patients With Metastatic Breast Cancer

Trial Profile

Phase 1b/2 Study to Evaluate Antibody-Drug Conjugate Sacituzumab Govitecan in Combination With PARP Inhibitor Talazoparib in Patients With Metastatic Breast Cancer

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 04 Jul 2024

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At a glance

  • Drugs Sacituzumab govitecan (Primary) ; Talazoparib (Primary)
  • Indications Advanced breast cancer; HER2 negative breast cancer; Triple negative breast cancer
  • Focus Adverse reactions

Most Recent Events

  • 04 Jun 2024 Results (n=26) assessing safety and efficacy of Sequential combination of sacituzumab govitecan and talazoparib in metastatic triple negative breast cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology
  • 28 Mar 2024 Planned End Date changed from 1 Dec 2024 to 1 Dec 2026.
  • 28 Mar 2024 Planned primary completion date changed from 1 Dec 2023 to 1 Dec 2025.

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