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A Phase 3 Multicenter, Randomized, Open Label, Active-controlled, Study of AMG 510 Versus Docetaxel for the Treatment of Previously Treated Locally Advanced and Unresectable or Metastatic NSCLC Subjects With Mutated KRAS p.G12C

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Trial Profile

A Phase 3 Multicenter, Randomized, Open Label, Active-controlled, Study of AMG 510 Versus Docetaxel for the Treatment of Previously Treated Locally Advanced and Unresectable or Metastatic NSCLC Subjects With Mutated KRAS p.G12C

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 27 Jul 2026

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At a glance

  • Drugs Sotorasib (Primary) ; Docetaxel
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms CodeBreak 200
  • Sponsors Amgen

Most Recent Events

  • 22 Jul 2026 Status changed from active, no longer recruiting to completed.
  • 30 Apr 2026 Planned End Date changed from 29 May 2026 to 24 Jun 2026.
  • 27 Mar 2026 Planned End Date changed from 25 Feb 2026 to 29 May 2026.

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