An Open-label, Active-Controlled, Safety and Efficacy Study of Oral Baricitinib in Patients from 2 Years to Less Than 18 Years Old with Active Juvenile Idiopathic Arthritis-Associated Uveitis or Chronic Anterior Antinuclear Antibody Positive Uveitis
Latest Information Update: 17 Dec 2024
At a glance
- Drugs Baricitinib (Primary) ; Adalimumab
- Indications Anterior uveitis; Uveitis
- Focus Registrational; Therapeutic Use
- Acronyms JUVE-BRIGHT
- Sponsors Eli Lilly and Company
Most Recent Events
- 13 Dec 2024 Planned End Date changed from 21 Jul 2028 to 1 Jul 2028.
- 15 Jun 2024 Primary endpoint (Percentage of Responders) has not been met, according to results presented at the 25th Annual Congress of the European League Against Rheumatism.
- 15 Jun 2024 Results (n=29) assessing the efficacy and safety of baricitinib when administered to paediatric patients with active JIA-U or chronic anterior ANA-positive uveitis, who had an inadequate response to MTX or bDMARDs and are receiving topical corticosteroid eye drops at a stable dose, presented at the 25th Annual Congress of the European League Against Rheumatism.