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Combination of Checkpoint Inhibition and IDO1 Inhibition Together With Standard Radiotherapy or Chemoradiotherapy in Newly Diagnosed Glioblastoma. A Phase 1 Clinical and Translational Trial

Trial Profile

Combination of Checkpoint Inhibition and IDO1 Inhibition Together With Standard Radiotherapy or Chemoradiotherapy in Newly Diagnosed Glioblastoma. A Phase 1 Clinical and Translational Trial

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 08 Jul 2025

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At a glance

  • Drugs Linrodostat (Primary) ; Nivolumab (Primary) ; Temozolomide
  • Indications Glioblastoma; Glioma
  • Focus Adverse reactions

Most Recent Events

  • 29 Jun 2025 Planned primary completion date changed from 15 Feb 2025 to 15 Feb 2027.
  • 15 Aug 2024 Planned End Date changed from 1 Jun 2025 to 1 Jun 2027.
  • 15 Aug 2024 Planned primary completion date changed from 22 Feb 2024 to 15 Feb 2025.

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