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To study effects of Upadacitinib Coadministration on the Pharmacokinetics of Sensitive Cytochrome P450 Probe Substrates: A Study With the Modified Cooperstown 5+1 Cocktail

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Trial Profile

To study effects of Upadacitinib Coadministration on the Pharmacokinetics of Sensitive Cytochrome P450 Probe Substrates: A Study With the Modified Cooperstown 5+1 Cocktail

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 12 Aug 2019

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At a glance

  • Drugs Upadacitinib (Primary) ; Caffeine; Dextromethorphan; Midazolam; Omeprazole; Vitamin K; Warfarin
  • Indications Ankylosing spondylitis; Atopic dermatitis; Crohn's disease; Giant cell arteritis; Juvenile rheumatoid arthritis; Psoriatic arthritis; Rheumatoid arthritis; Systemic lupus erythematosus; Ulcerative colitis
  • Focus Adverse reactions; Pharmacokinetics

Most Recent Events

  • 12 Aug 2019 New trial record
  • 05 Aug 2019 Results assessing effects to characterize the effects of upadacitinib on in vivo activity of different cytochrome published in the Journal of Clinical Pharmacology

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