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An Open-label, Single Sequence Crossover, Drug Interaction Study to Investigate the Effect of Linerixibat (GSK2330672) on Plasma Concentrations of Obeticholic Acid and Conjugates in Healthy Participants

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Trial Profile

An Open-label, Single Sequence Crossover, Drug Interaction Study to Investigate the Effect of Linerixibat (GSK2330672) on Plasma Concentrations of Obeticholic Acid and Conjugates in Healthy Participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Jul 2023

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At a glance

  • Drugs Linerixibat (Primary) ; Obeticholic acid
  • Indications Cholestasis; Primary biliary cirrhosis; Pruritus; Type 2 diabetes mellitus
  • Focus Pharmacokinetics
  • Sponsors GlaxoSmithKline; GSK

Most Recent Events

  • 09 Dec 2019 Status changed from active, no longer recruiting to completed.
  • 20 Oct 2019 Status changed from recruiting to active, no longer recruiting.
  • 10 Sep 2019 Status changed from not yet recruiting to recruiting.

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