A Phase II, Multicenter, Randomized, Open Label Two Arm Study Evaluating the Effect of Crizanlizumab + Standard of Care and Standard of Care Alone on Renal Function in Sickle Cell Disease Patients ≥ 16 Years With Chronic Kidney Disease Due to Sickle Cell Nephropathy (STEADFAST)
Latest Information Update: 11 Jun 2024
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At a glance
- Drugs Crizanlizumab (Primary) ; ACE inhibitors; Angiotensin receptor antagonists; Hydroxycarbamide
- Indications Sickle cell anaemia
- Focus Pharmacodynamics
- Acronyms STEADFAST
- Sponsors Novartis; Novartis Pharmaceuticals
- 08 Mar 2024 This trial has been discontinued in Italy, according to European Clinical Trials Database record.
- 22 May 2023 Status changed from active, no longer recruiting to completed.
- 18 May 2023 This trial has been completed in Ireland (Date of the global end of the trial: 20- Mar 2023).