A Phase 3, Open-label Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy in Subjects With Cystic Fibrosis Who Are Heterozygous for the F508del Mutation and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)
Latest Information Update: 18 Jan 2024
At a glance
- Drugs Elexacaftor/ivacaftor/tezacaftor (Primary) ; Ivacaftor
- Indications Cystic fibrosis
- Focus Adverse reactions; Registrational
- Sponsors Vertex Pharmaceuticals
Most Recent Events
- 20 Jan 2023 Status changed from active, no longer recruiting to completed.
- 29 Aug 2022 Planned End Date changed from 1 Aug 2022 to 1 Jan 2023.
- 29 Aug 2022 Planned primary completion date changed from 1 Aug 2022 to 1 Jan 2023.