A Phase 2 Study to Evaluate the Safety and Tolerability of IMR-687 in Subjects With Beta Thalassemia
Latest Information Update: 14 Sep 2023
At a glance
- Drugs Tovinontrine (Primary)
- Indications Beta-thalassaemia
- Focus Adverse reactions
- Acronyms FORTE
- Sponsors Imara Inc
- 09 May 2022 Status changed from active, no longer recruiting to discontinued. Reason the study was stopped: IMR-BTL-201demonstrated that while IMR-687 was generally well-tolerated, it failed to show any meaningful benefit in transfusion burden or improvement in most disease-related biomarkers. So, the sponsor has decided to discontinue this study
- 20 Apr 2022 This trial has been discontinued in Greece (End date: 6th April 2022)according to European Clinical Trials Database record.
- 05 Apr 2022 According to an Imara Inc media release, the company has decided to discontinue Ardent and Forte during the second quarter as well as the further development of tovinontrine in sickle cell disease and beta-thalassemia.