Trial Profile

A Multi-Center Phase 2 Study of Combined Modality Treatment With Ruxolitinib, Decitabine, and Donor Lymphocyte Infusion for Post-Transplant Relapse of AML or MDS

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 09 Nov 2023

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At a glance

Drugs Decitabine (Primary) ; Ruxolitinib (Primary) ; Lymphocyte replacements
Indications Acute myeloid leukaemia; Myelodysplastic syndromes
Focus Therapeutic Use

01 May 2023 Results assessing efficacy of of 10-Day Decitabine, Dose-Escalated Donor Lymphocyte Infusion, and Ruxolitinib for Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes after Allogeneic Hematopoietic Cell Transplantation published in the Transplantation and Cellular Therapy
02 Nov 2022 Status changed from active, no longer recruiting to completed.
16 Feb 2022 Planned primary completion date changed from 1 Jan 2025 to 1 Jul 2022.

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