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An Open Label Randomized Phase 2 Trial of Amcenestrant (SAR439859), Versus Endocrine Monotherapy as Per Physician's Choice in Patients With Estrogen Receptor-positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer With Prior Exposure to Hormonal Therapies

Trial Profile

An Open Label Randomized Phase 2 Trial of Amcenestrant (SAR439859), Versus Endocrine Monotherapy as Per Physician's Choice in Patients With Estrogen Receptor-positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer With Prior Exposure to Hormonal Therapies

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 29 Jan 2025

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At a glance

  • Drugs Amcenestrant (Primary) ; Anastrozole; Exemestane; Fulvestrant; Letrozole; Tamoxifen
  • Indications Adenocarcinoma; Advanced breast cancer; HER2 negative breast cancer; Male breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms AMEERA-3
  • Sponsors Sanofi

Most Recent Events

  • 31 Dec 2024 Planned End Date changed from 29 Nov 2024 to 1 Jan 2025.
  • 22 Oct 2024 Planned End Date changed from 30 Sep 2024 to 29 Nov 2024.
  • 04 Apr 2024 Planned End Date changed from 29 Apr 2024 to 30 Sep 2024.

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