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Ruxolitinib in Combination With Corticosteroid as First Line Therapy for the Treatment of High Risk Acute Graft-Versus-Host Disease

Trial Profile

Ruxolitinib in Combination With Corticosteroid as First Line Therapy for the Treatment of High Risk Acute Graft-Versus-Host Disease

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 30 Nov 2023

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At a glance

  • Drugs Ruxolitinib (Primary) ; Methylprednisolone
  • Indications Graft-versus-host disease
  • Focus Therapeutic Use

Most Recent Events

  • 25 Nov 2023 Status changed from recruiting to completed.
  • 13 Dec 2022 Results assessing the safety and efficacy of corticosteroids (2mg/kg/day) alone versus ruxolitinb combined with reduced dose of corticosteroids (1mg/kg/day) in patients with high-risk aGVHD after allogeneic peripheral blood stem cell transplantation. presented at the 64th American Society of Hematology Annual Meeting and Exposition
  • 06 Jun 2022 Trial design published in the Trials

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