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An Open Label, Randomized Controlled Trial to Establish the Efficacy and Safety of a Study Strategy Consisting of 6 Months of Bedaquiline (BDQ), Delamanid (DLM), and Linezolid (LNZ), With Levofloxacin (LVX) and Clofazimine (CFZ) Compared to the Current South African Standard of Care (Control Strategy) for 9 Months for the Treatment of Rifampicin Resistant Tuberculosis (RR-TB)

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An Open Label, Randomized Controlled Trial to Establish the Efficacy and Safety of a Study Strategy Consisting of 6 Months of Bedaquiline (BDQ), Delamanid (DLM), and Linezolid (LNZ), With Levofloxacin (LVX) and Clofazimine (CFZ) Compared to the Current South African Standard of Care (Control Strategy) for 9 Months for the Treatment of Rifampicin Resistant Tuberculosis (RR-TB)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 30 Aug 2024

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At a glance

  • Drugs Bedaquiline (Primary) ; Clofazimine (Primary) ; Delamanid (Primary) ; Levofloxacin (Primary) ; Linezolid (Primary) ; Ethambutol; Isoniazid; Pyrazinamide
  • Indications Pulmonary tuberculosis
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms BEAT-Tuberculosis

    • Most Recent Events

    • 28 Aug 2024 Status changed from active, no longer recruiting to completed.
    • 20 Oct 2022 Status changed from recruiting to active, no longer recruiting.
    • 20 Oct 2022 Planned End Date changed from 1 Mar 2023 to 1 Jun 2023.

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