Trial Profile

The ABNL-MARRO 001 Study: A Phase 1/2 Study of Active Myeloid Target Compound Combinations in MDS/MPN Overlap Syndromes.

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 27 Feb 2026

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At a glance

Drugs Cedazuridine/decitabine (Primary) ; INCB 59872 (Primary) ; Itacitinib (Primary) ; Uzansertib (Primary)
Indications Myelodysplastic syndromes; Myeloproliferative disorders
Focus Adverse reactions; Therapeutic Use
Acronyms ABNL MARRO 001

Most Recent Events

24 Feb 2026 Planned number of patients changed from 117 to 94.
24 Feb 2026 Planned End Date changed from 1 Aug 2025 to 1 Dec 2027.
24 Feb 2026 Planned primary completion date changed from 1 Aug 2024 to 1 Aug 2027.

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