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A Phase 1/2a Clinical Trial of BI-1206, a Monoclonal Antibody to CD32b (FcγRIIB), in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors Previously Treated with Anti-PD-1 or Anti-PD-L1 Antibodies (KEYNOTE-A04)

Trial Profile

A Phase 1/2a Clinical Trial of BI-1206, a Monoclonal Antibody to CD32b (FcγRIIB), in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors Previously Treated with Anti-PD-1 or Anti-PD-L1 Antibodies (KEYNOTE-A04)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 09 Feb 2025

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At a glance

  • Drugs BI 1206 (Primary) ; BI 1206 (Primary) ; Pembrolizumab (Primary)
  • Indications Malignant melanoma; Non-small cell lung cancer; Solid tumours; Uveal melanoma
  • Focus Adverse reactions
  • Acronyms KEYNOTE-A04
  • Sponsors BioInvent International

Most Recent Events

  • 08 Jan 2025 According to BioInvent International media release, the company is looking forward to further data from the study next year.
  • 03 Jan 2025 Planned number of patients changed from 90 to 197.
  • 03 Jan 2025 Planned End Date changed from 1 Jan 2026 to 1 Nov 2027.

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