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A Randomized, Open Label, Single / Multiple Dose, Crossover Phase 1, Study to Evaluate Drug-Drug Interaction of DWP16001 in Combination With Metformin in Healthy Male Adults

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Trial Profile

A Randomized, Open Label, Single / Multiple Dose, Crossover Phase 1, Study to Evaluate Drug-Drug Interaction of DWP16001 in Combination With Metformin in Healthy Male Adults

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 02 May 2023

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At a glance

  • Drugs Enavogliflozin (Primary) ; Gemigliptin (Primary) ; Metformin (Primary)
  • Indications Metabolic disorders; Type 2 diabetes mellitus
  • Focus Pharmacokinetics
  • Sponsors Daewoong Pharmaceutical

    • Most Recent Events

    • 24 Mar 2023 Results assessing pharmacokinetics (PK) and pharmacodynamics (PD) interaction of DWP16001 with gemigliptin and metformin presented at the 124th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics.
    • 10 Dec 2022 Results assessing Pharmacokinetic and Pharmacodynamic Interaction of DWP16001, an SGLT2 Inhibitor, with Gemigliptin and Metformin in Healthy Adults published in the British Journal of Clinical Pharmacology
    • 24 Nov 2022 Results assessing Pharmacokinetic and Pharmacodynamic Interaction Between DWP16001, an SGLT2 Inhibitor, and Metformin in Healthy Subjects published in the British Journal of Clinical Pharmacology

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