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A Phase 2 Study of TGF-β Inhibition (Vactosertib) With Anti-PD-L1 (Durvalumab) in Patients With Advanced or Recurrent Urothelial Carcinoma Failing to Achieve Response With Checkpoint Inhibition

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A Phase 2 Study of TGF-β Inhibition (Vactosertib) With Anti-PD-L1 (Durvalumab) in Patients With Advanced or Recurrent Urothelial Carcinoma Failing to Achieve Response With Checkpoint Inhibition

Status: Withdrawn prior to enrolment
Phase of Trial: Phase II

Latest Information Update: 11 Dec 2024

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At a glance

  • Drugs Durvalumab (Primary) ; Vactosertib (Primary)
  • Indications Bladder cancer; Carcinoma; Pelvic cancer; Ureteral neoplasms; Urethral cancer; Urogenital cancer
  • Focus Therapeutic Use
  • Sponsors MedPacto

    • Most Recent Events

    • 09 Dec 2024 Status changed from not yet recruiting to withdrawn prior to enrolment.
    • 22 Sep 2021 Planned End Date changed from 30 Dec 2023 to 30 Dec 2024.
    • 22 Sep 2021 Planned primary completion date changed from 30 Dec 2022 to 30 Dec 2023.

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