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Safety, Tolerability, and Efficacy of Once Weekly Carfilzomib in Combination With Daratumumab, Lenalidomide and Dexamethasone, in Transplant-ineligible Multiple Myeloma Patients Non-responsive to a Bortezomib Based Induction

Trial Profile

Safety, Tolerability, and Efficacy of Once Weekly Carfilzomib in Combination With Daratumumab, Lenalidomide and Dexamethasone, in Transplant-ineligible Multiple Myeloma Patients Non-responsive to a Bortezomib Based Induction

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 11 Jan 2023

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At a glance

  • Drugs Carfilzomib (Primary) ; Daratumumab (Primary) ; Dexamethasone (Primary) ; Dexamethasone (Primary) ; Lenalidomide (Primary) ; Anticoagulants
  • Indications Multiple myeloma
  • Focus Adverse reactions
  • Acronyms KyDaR
  • Most Recent Events

    • 13 Dec 2022 Results assessing the safety and efficacy of a quadruple salvage regimen of carfilzomib, lenalidomide, dexamethasone, daratumumab (KRD-D) in myeloma Pts and to identify molecular pathways of refractoriness based on transcriptional signatures with functional high presented at the 64th American Society of Hematology Annual Meeting and Exposition
    • 26 Jan 2022 Status changed from active, no longer recruiting to completed.
    • 17 Jun 2020 Status changed from recruiting to active, no longer recruiting.

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