Trial Profile

A Phase 2, Open Label, Multiple Center Study to Evaluate the Safety, Tolerability, and Efficacy of CM-101 Administered for 12 Weeks in Adult Subjects with Primary Sclerosing Cholangitis

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 08 Jul 2025

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At a glance

30 Jun 2025 According to a Chemomab Therapeutics media release, rececent findings from this Phase 2 SPRING trial suggest that nebokitug may have disease-modifying potential in PSC and support advancement to a Phase 3 registration trial.
30 Jun 2025 Results published in the Media Release
30 Jun 2025 According to a Chemomab Therapeutics media release, company announced that data from the company's Phase 2 SPRING trial of nebokitug (CM-101) in patients with primary sclerosing cholangitis (PSC) was presented in an oral session1 at BSG Live 25, the annual scientific meeting of the British Society for Gastroenterology, in Glasgow, UK.

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