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A Phase Ib/II, Open-label, Multicenter Study of Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First-line Therapy in Metastatic Microsatellite-stable Colorectal Cancer (COLUMBIA-1)

Trial Profile

A Phase Ib/II, Open-label, Multicenter Study of Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First-line Therapy in Metastatic Microsatellite-stable Colorectal Cancer (COLUMBIA-1)

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 21 Nov 2023

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At a glance

  • Drugs Durvalumab (Primary) ; Oleclumab (Primary) ; Bevacizumab; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Colorectal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms COLUMBIA-1
  • Sponsors AstraZeneca AB; MedImmune

Most Recent Events

  • 13 Nov 2023 Status changed from completed to discontinued.
  • 10 Mar 2023 Status changed from active, no longer recruiting to completed.
  • 04 Sep 2022 The trial has been discontinued in Spain, according to European Clinical Trials Database

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