A Randomized, Multicenter, Open-Label, Phase 3 Study to Evaluate the Efficacy and Safety of Acalabrutinib Versus Chlorambucil Plus Rituximab in Subjects With Previously Untreated Chronic Lymphocytic Leukemia
Latest Information Update: 02 May 2025
At a glance
- Drugs Acalabrutinib (Primary) ; Chlorambucil; Rituximab
- Indications Chronic lymphocytic leukaemia
- Focus Registrational; Therapeutic Use
- Acronyms ChangE
- Sponsors AstraZeneca
Most Recent Events
- 25 Apr 2025 Planned End Date changed from 31 Mar 2025 to 1 Jan 2027.
- 30 Jan 2025 Planned End Date changed from 29 Nov 2024 to 31 Mar 2025.
- 07 Nov 2024 According to AstraZeneca media release, result data from this trial will be presented at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition 7 to 10 December 2024.