A Phase I Open Label First in Human Dose Escalation of the Immunoproteasome Inhibitor M3258 as a Single Agent and Expansion Study of M3258 in Combination With Dexamethasone in Participants With Relapsed Refractory Multiple Myeloma
Latest Information Update: 27 Mar 2023
At a glance
- Drugs M 3258 (Primary) ; Dexamethasone
- Indications Multiple myeloma
- Focus Adverse reactions; First in man; Therapeutic Use
- Sponsors EMD Serono Research & Development Institute
Most Recent Events
- 10 May 2021 Status changed from recruiting to discontinued given the changed therapeutic landscape, lack of recruitment and totality of the data collected so far.
- 03 Nov 2020 Planned End Date changed from 6 Apr 2021 to 4 Jun 2021.
- 03 Nov 2020 Planned primary completion date changed from 6 Apr 2021 to 4 Jun 2021.