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V-FAST: A Phase 1b Master Trial to Investigate CPX-351 Combined With Various Targeted Agents in Subjects With Previously Untreated Acute Myeloid Leukemia

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V-FAST: A Phase 1b Master Trial to Investigate CPX-351 Combined With Various Targeted Agents in Subjects With Previously Untreated Acute Myeloid Leukemia

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 18 Oct 2023

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At a glance

  • Drugs Cytarabine/daunorubicin (Primary) ; Enasidenib; Midostaurin; Venetoclax
  • Indications Acute myeloid leukaemia
  • Focus Adverse reactions
  • Acronyms V-FAST
  • Sponsors Jazz Pharmaceuticals Inc

    • Most Recent Events

    • 12 Oct 2023 Status changed from active, no longer recruiting to completed.
    • 13 Dec 2022 Preliminary Results of outcomes for a subgroup analysis based on the presence of a FLT3 internal tandem duplication and/or tyrosine kinase domain mutation within the cohort of adults primarily with de novo AML who were treated with CPX-351 + MID , presented at the 64th American Society of Hematology Annual Meeting and Exposition
    • 03 Nov 2022 According to a Jazz Pharmaceuticals media release, a subgroup analysis from Arm B of the trial will be presented at the American Society of Hematology (ASH) Annual Meeting.

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