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An Open, Single Arm, Multicenter, Exploratory Phase II Clinical Trial of Anlotinib Hydrochloride Capsules Combined With CAPEOX in RAS and BRAF Wild-type Patients With Metastatic Colorectal Carcinoma as 1st Therapy

Trial Profile

An Open, Single Arm, Multicenter, Exploratory Phase II Clinical Trial of Anlotinib Hydrochloride Capsules Combined With CAPEOX in RAS and BRAF Wild-type Patients With Metastatic Colorectal Carcinoma as 1st Therapy

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 27 Feb 2024

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At a glance

  • Drugs Catequentinib (Primary) ; Capecitabine; Oxaliplatin
  • Indications Carcinoma; Colon cancer; Colorectal cancer; Liver metastases; Rectal cancer
  • Focus Therapeutic Use
  • Acronyms ALTER-C-002

Most Recent Events

  • 20 Jan 2024 Updated overall survival results (at the data cutoff of May 29, 2023) presented at the 2024 Gastrointestinal Cancers Symposium.
  • 06 Jun 2023 Results investigating the value of ctDNA in predicting treatment response and PFS in mCRC patients treated with anlotinib plus CAPEOX as first-line therapy, presented at the 59th Annual Meeting of the American Society of Clinical Oncology
  • 21 Jan 2023 Updated results (at the data cutoff :19 August 2022) presented at the 2023 Gastrointestinal Cancers Symposium.

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