Trial Profile

A Double-Blind, Placebo-Controlled, Phase 2 Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx, an Antisense Inhibitor Administered Subcutaneously for 8 Weeks to Hypertensive Subjects With Uncontrolled Blood Pressure

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 20 Jan 2023

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At a glance

17 May 2021 Primary endpoint (Percent Change in Plasma Angiotensinogen (AGT) from Baseline to Study Day 57 (Study Week 9) Compared to Placebo) has been met as per results presented at the 70th Annual Scientific Session of the American College of Cardiology
17 May 2021 Results presented at the 70th Annual Scientific Session of the American College of Cardiology
15 Sep 2020 Status changed from active, no longer recruiting to completed.

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